产品货号：
JN0797
中文名称：
重组人胰岛素降解酶(IDE)
英文名称：
Recombinant Human Insulin-Degrading Enzyme
产品规格：
10μg|50μg|500μg|1mg
发货周期：
1～3天
产品价格：
询价
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met42-Leu1019在C端含有His标签。
蛋白编号：P14735
蛋白别称：Insulin-Degrading Enzyme;Abeta-Degrading Protease;Insulin Protease;Insulinase;Insulysin;IDE
分子量：114.25 KDa
表观分子量：120 KDa,reducing conditions
纯度：＞95%(还原性SDS-PAGE)
内毒素：＜1 EU/μg（LAL）
保存液：20mM Tris-HCl,150mM NaCl,0.05% Brij35,10% Glycerol,pH7.5。
保存：-70℃，有效期6个月。开盖后无菌条件下可保存3个月，减少反复冻融。
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family.IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence.IDE plays a role in the cellular breakdown of insulin,IAPP,glucagon,bradykinin,kallidin,and other peptides,and thereby plays a role in intercellular peptide signaling.IDE degrades amyloid formed by APP and IAPP.IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia.IDE,which migrates at 110kDa during gel electrophoresis under denaturing conditions,has since been shown to have additional substrates,including the signaling peptides glucagon,TGF α and β-endorphin.
相关搜索：重组人胰岛素降解酶(IDE)，胰岛素降解酶，Insulin-Degrading，Insulinase，Insulysin，Recombinant Human Insulin-Degrading Enzyme
蛋白编号：P14735
蛋白别称：Insulin-Degrading Enzyme;Abeta-Degrading Protease;Insulin Protease;Insulinase;Insulysin;IDE
分子量：114.25 KDa
表观分子量：120 KDa,reducing conditions
纯度：＞95%(还原性SDS-PAGE)
内毒素：＜1 EU/μg（LAL）
保存液：20mM Tris-HCl,150mM NaCl,0.05% Brij35,10% Glycerol,pH7.5。
保存：-70℃，有效期6个月。开盖后无菌条件下可保存3个月，减少反复冻融。
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family.IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence.IDE plays a role in the cellular breakdown of insulin,IAPP,glucagon,bradykinin,kallidin,and other peptides,and thereby plays a role in intercellular peptide signaling.IDE degrades amyloid formed by APP and IAPP.IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia.IDE,which migrates at 110kDa during gel electrophoresis under denaturing conditions,has since been shown to have additional substrates,including the signaling peptides glucagon,TGF α and β-endorphin.
相关搜索：重组人胰岛素降解酶(IDE)，胰岛素降解酶，Insulin-Degrading，Insulinase，Insulysin，Recombinant Human Insulin-Degrading Enzyme